Absolute requirement of GDNF for adult catecholaminergic neuron survival
نویسندگان
چکیده
منابع مشابه
GDNF and protection of adult central catecholaminergic neurons.
Neurotrophic factors are small proteins necessary for neuron survival and maintenance of phenotype. They are considered as promising therapeutic tools for neurodegenerative diseases. The glial cell line-derived neurotrophic factor (GDNF) protects catecholaminergic cells from toxic insults; thus, its potential therapeutic applicability in Parkinson's disease has been intensely investigated. In r...
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ژورنال
عنوان ژورنال: Nature Neuroscience
سال: 2008
ISSN: 1097-6256,1546-1726
DOI: 10.1038/nn.2136